A year after the death of his friend and partner Sherlock Holmes, Dr. John Watson resumes his medical career at a clinic dedicated to the treatment of rare diseases. However, he soon finds that his old life is not done with him yet.

A group of contestants move into the Big Brother house, where they nominate each other to be evicted by public vote. The last person remaining will take home a large cash prize, while the others take home nothing.

Follows the inner workings of the New York Field Office of the FBI, as they fight to keep New York City and the country safe.